Real-time PCR was used to assess the expression of NT-pro BNP, BNP and ANP genes after inducing MI (by blocking left coronary artery by surgery). Methods: Twelve Wistar male rats of 10 weeks old and mean weight 250-300gr were allocated in two groups with six rats in each group of experimental (60 minutes interval running on a treadmill, each cycle including four minutes of running with an intensity of 80-95% VO2max and two minutes of active recovery with a 45-50% VO2max intensity, three days a week for six weeks) and control group (without any precedent of training). Atrial and ventricular natriuretic peptides (ANP & BNP) are strong indicators of myocardial infarction.This study aimed to evaluate the effect of six weeks intensive periodic training on the NT-pro BNP, BNP and ANP in rats after myocardial infarction. Background: Myocardial infarction is the irreversible cell death of a part of cardiac muscle as a result of a cut in blood flow.
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